Dentin inhibits the antibacterial effect of new and conventional endodontic irrigants.

摘要: Introduction: This in vitro study aimed to compare the antibacterial effect of a new irrigant, QMiX, with that conventional irrigation solutions presence or absence dentin powder. Methods: Dentin powder was prepared from bovine incisors and sterilized. The following irrigants were tested against Enterococcus faecalis (ATCC 29212): 6% sodium hypochlorite (NaOCl), 1% NaOCl, 2% chlorhexidine gluconate (CHX), 17% EDTA. Sterilized saline solution used as negative control. Survival bacteria exposed monitored under planktonic conditions. Colony-forming units counted, log-transformed numbers analyzed by using Kruskal-Wallis Mann-Whitney tests. P values less than.05 considered significant. Results: In dentin, after 10 seconds contact bacterial suspension, NaOCl showed lowest count; difference control After 30 seconds, displayed 0 colony-forming per milliliter, whereas QMiX reduced number colonies comparison 1 minute, both concentrations presented no growth colonies, but EDTA CHX had counts similar significant inhibitory on (10 seconds), minute), minute). 6 hours, killed all bacteria, regardless dentin. Conclusions: Six percent most effective irrigant E. faecalis. Saline measurable effect. delayed activity did not completely prevent their action.