Another zinc finger in the pie of CD4-CD8 lineage choice
作者： Kensuke Takada , Yousuke Takahama
DOI: 10.1038/NI0510-370
关键词:
摘要: The 'choice' between the CD4+CD8− and CD4−CD8+ T cell lineage involves genomic specification via a set of transcription factors. A new study shows that zinc-finger protein MAZR is another member this factor network.
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sci-hub.se 参考文章(12)
M Fedele, R Franco, G Salvatore, MP Paronetto, F Barbagallo, R Pero, L Chiariotti, C Sette, D Tramontano, G Chieffi, A Fusco, P Chieffi, PATZ1 gene has a critical role in the spermatogenesis and testicular tumours. The Journal of Pathology. ,vol. 215, pp. 39- 47 ,(2008) , 10.1002/PATH.2323
Ivan Bilic, Christina Koesters, Bernd Unger, Masayuki Sekimata, Arnulf Hertweck, Romana Maschek, Christopher B Wilson, Wilfried Ellmeier, Negative regulation of CD8 expression via CD8 enhancer-mediated recruitment of the zinc finger protein MAZR Nature Immunology. ,vol. 7, pp. 392- 400 ,(2006) , 10.1038/NI1311
Amélie Collins, Dan R. Littman, Ichiro Taniuchi, RUNX proteins in transcription factor networks that regulate T-cell lineage choice Nature Reviews Immunology. ,vol. 9, pp. 106- 115 ,(2009) , 10.1038/NRI2489
Takeshi Nitta, Shigeo Murata, Katsuhiro Sasaki, Hideki Fujii, Adiratna Mat Ripen, Naozumi Ishimaru, Shigeo Koyasu, Keiji Tanaka, Yousuke Takahama, Thymoproteasome Shapes Immunocompetent Repertoire of CD8+ T Cells Immunity. ,vol. 32, pp. 29- 40 ,(2010) , 10.1016/J.IMMUNI.2009.10.009
Parinaz Aliahmad, Jonathan Kaye, Development of all CD4 T lineages requires nuclear factor TOX. Journal of Experimental Medicine. ,vol. 205, pp. 245- 256 ,(2008) , 10.1084/JEM.20071944
Xi He, Kyewon Park, Haitao Wang, Xiao He, Yi Zhang, Xiang Hua, Yi Li, Dietmar J. Kappes, CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus Immunity. ,vol. 28, pp. 346- 358 ,(2008) , 10.1016/J.IMMUNI.2008.02.006
Xiao He, Xi He, Vibhuti P. Dave, Yi Zhang, Xiang Hua, Emmanuelle Nicolas, Weihong Xu, Bruce A. Roe, Dietmar J. Kappes, The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment Nature. ,vol. 433, pp. 826- 833 ,(2005) , 10.1038/NATURE03338
R. Setoguchi, M. Tachibana, Y. Naoe, S. Muroi, K. Akiyama, C. Tezuka, T. Okuda, I. Taniuchi, Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science. ,vol. 319, pp. 822- 825 ,(2008) , 10.1126/SCIENCE.1151844
Shinya Sakaguchi, Matthias Hombauer, Ivan Bilic, Yoshinori Naoe, Alexandra Schebesta, Ichiro Taniuchi, Wilfried Ellmeier, The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes Nature Immunology. ,vol. 11, pp. 442- 448 ,(2010) , 10.1038/NI.1860
Lie Wang, Kathryn F Wildt, Jinfang Zhu, Xianyu Zhang, Lionel Feigenbaum, Lino Tessarollo, William E Paul, B J Fowlkes, Rémy Bosselut, Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nature Immunology. ,vol. 9, pp. 1122- 1130 ,(2008) , 10.1038/NI.1647