Adrenal cortical carcinoma
作者： Swamy Venkatesh , Robert C. Hickey , Rena V. Sellin , Jose F. Fernandez , Naguib A. Samaan
DOI: 10.1002/1097-0142(19890801)64:3<765::AID-CNCR2820640333>3.0.CO;2-I
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摘要: The records of 110 patients (58 females and 52 males) with histologically proven adrenal cortical carcinoma were studied. Fifty-six (50.9%) had abdominal symptoms 33 (30.0%) a palpable mass. Surgery for localized regional disease was associated disease-free survival time at least 2 years in 28 the 50 (56%) patients. Abdominal radiotherapy, systemic chemotherapy, 1,1 dichloro-2 (O-chlorophenyl)-2 (P-chlorophenyl) ethane (OPDDD) effective three 19 (15.8%) patients, 31 (9.7%) 21 72 (29.2%) respectively. Combined radiotherapy OPDDD did not confer any additional benefit over alone. Six seven who received as adjuvant treatment are still alive 1 to 4 years. Distant metastases occurred most commonly lungs, liver, peritoneum, lymph nodes, bones. Only 23% survived 5 or more. We conclude that early diagnosis complete surgical excision offer best prospects long-term efficacy needs be evaluated further.
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