Listeria ivanovii is capable of cell-to-cell spread involving actin polymerization.
作者： I Karunasagar , G Krohne , W Goebel
DOI: 10.1128/IAI.61.1.162-169.1993
关键词:
摘要: Listeria ivanovii has been considered to be pathogenic animals but rarely found associated with human infections. It claimed that L. lacks the actA gene, which in monocytogenes encodes a protein required for interaction host cell actin. Using fluorescence microscopy and electron microscopy, we demonstrate can invade mammalian cells, lyse phagosomal membrane, polymerize actin, reorganize actin form tails, spread from cell. However, no DNA homologous gene could detected by polymerase chain reaction. Further, 90-kDa surface is encoded actA. Despite ability cell, differed significantly being unable plaques on monolayers of 3T3 fibroblast cells.
sci-hub.st 参考文章(17)
P. Berche, J. -L. Gaillard, S. Richard, Invasiveness and intracellular growth of Listeria monocytogenes Infection. ,vol. 16, pp. S145- S148 ,(1988) , 10.1007/BF01639738
E. Domann, J. Wehland, M. Rohde, S. Pistor, M. Hartl, W. Goebel, M. Leimeister-Wächter, M. Wuenscher, T. Chakraborty, A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin. The EMBO Journal. ,vol. 11, pp. 1981- 1990 ,(1992) , 10.1002/J.1460-2075.1992.TB05252.X
M Kuhn, M C Prévost, J Mounier, P J Sansonetti, A nonvirulent mutant of Listeria monocytogenes does not move intracellularly but still induces polymerization of actin. Infection and Immunity. ,vol. 58, pp. 3477- 3486 ,(1990) , 10.1128/IAI.58.11.3477-3486.1990
J A Vazquez-Boland, C Kocks, S Dramsi, H Ohayon, C Geoffroy, J Mengaud, P Cossart, Nucleotide sequence of the lecithinase operon of Listeria monocytogenes and possible role of lecithinase in cell-to-cell spread. Infection and Immunity. ,vol. 60, pp. 219- 230 ,(1992) , 10.1128/IAI.60.1.219-230.1992
M. Leimeister-Wachter, C. Haffner, E. Domann, W. Goebel, T. Chakraborty, Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 8336- 8340 ,(1990) , 10.1073/PNAS.87.21.8336
Alan Weeds, Actin-binding proteins--regulators of cell architecture and motility. Nature. ,vol. 296, pp. 811- 816 ,(1982) , 10.1038/296811A0
M. L. Bernardini, J. Mounier, H. d'Hauteville, M. Coquis-Rondon, P. J. Sansonetti, Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 3867- 3871 ,(1989) , 10.1073/PNAS.86.10.3867
G. A. Dabiri, J. M. Sanger, D. A. Portnoy, F. S. Southwick, Listeria monocytogenes moves rapidly through the host-cell cytoplasm by inducing directional actin assembly. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 6068- 6072 ,(1990) , 10.1073/PNAS.87.16.6068
J.-L. Gaillard, P. Berche, C. Frehel, E. Gouln, P. Cossart, Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci Cell. ,vol. 65, pp. 1127- 1141 ,(1991) , 10.1016/0092-8674(91)90009-N
Arturo Zychlinsky, Marie Christine Prevost, Philippe J. Sansonetti, Shigella flexneri induces apoptosis in infected macrophages Nature. ,vol. 358, pp. 167- 169 ,(1992) , 10.1038/358167A0