Parameters Associated With Endothelial Cell Density Variability After Descemet Membrane Endothelial Keratoplasty
作者： Silke Oellerich , Lisanne Ham , Laurence E. Frank , Sandra Gorges , Vincent J.A. Bourgonje
DOI: 10.1016/J.AJO.2019.10.017
关键词:
摘要: Purpose To evaluate which parameters may affect endothelial cell loss after Descemet membrane keratoplasty (DMEK) by comparing eyes in the low vs high quartile of over a follow-up period 4 years. Design Retrospective cohort study. Methods Donor density (ECD) decline was evaluated for 351 275 patients up to years DMEK Fuchs corneal dystrophy (FECD). Eyes with postoperative lower at all available moments were assigned Group 1 (n = 51) and those upper 2 42). Multinomial regression used assess covariates related greater ECD decline. Results Mean as compared preoperative donor entire study group 33 (±16)%, 36 (±17)%, 52 (±18)% 1, 6, 48 months postoperatively. Endothelial 12 (±7)%, 13 (±6)%, 26 (±8)% at, respectively, postoperatively, 59 (±10)%, 64 (±9)%, 75 (±5)% 2. Partial graft detachment, death cause cardiovascular/stroke (vs cancer), complications other than severity FECD (all P Conclusions completely attached operated an early stage show lowest
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