Surgical targets for dystonic tremor: considerations between the globus pallidus and ventral intermediate thalamic nucleus.

摘要: Dystonic tremor (DT) is characterized by coexisting and abnormal dystonic posturing in the same segment. DT often medically refractory DBS an important therapeutic option. However, optimal surgical target for remains uncertain with Vim, GPi zona incerta previously reported as effective. We retrospectively reviewed outcome data from all patients involving at least one upper extremity who underwent Vanderbilt University July 2006 to 2010. evaluated improvement of dystonia after their response was judged be maximal. Ten met inclusion criteria. Vim targeted four three had unilateral procedure bilateral DBS. every patient this subgroup. A combined performed two patients. The best results control were observed but they persisting mild dystonia. Patients average approximately 50% symptoms markedly improved. propose that a should considered coexistence severe may successfully controlled surgeries.