Circular RNAs: New Players in Gene Regulation

作者: Kalina Andreeva , Nigel G. F. Cooper

DOI: 10.4236/ABB.2015.66043

关键词:

摘要: The existence of circular RNAs (circRNAs) was demonstrated over 30 years ago. They did not gain much interest at the time because they appeared to be relatively rare when compared abundance canonical linear RNAs. However, more recent evidence suggests that circRNAs are abundant in cells and tissues possess intriguing biological properties. These developments have renewed our this novel class molecules. This report will provide an overview circRNAs, discuss how may modify understanding gene regulation indicate their most likely relevance health. from viruses, bacteria archaea scope report, we focused review on eukaryotes.

参考文章(51)
Junhua Gong, Zheng Cui, Li Li, Qiang Ma, Qiufang Wang, Yinhe Gao, Hao Sun, None, MicroRNA-25 promotes gastric cancer proliferation, invasion, and migration by directly targeting F-box and WD-40 Domain Protein 7, FBXW7. Tumor Biology. ,vol. 36, pp. 7831- 7840 ,(2015) , 10.1007/S13277-015-3510-3
Reza Naghavian, Kamran Ghaedi, Abbas Kiani-Esfahani, Mazdak Ganjalikhani-Hakemi, Masoud Etemadifar, Mohammad Hossein Nasr-Esfahani, miR-141 and miR-200a, Revelation of New Possible Players in Modulation of Th17/Treg Differentiation and Pathogenesis of Multiple Sclerosis PLOS ONE. ,vol. 10, pp. e0124555- ,(2015) , 10.1371/JOURNAL.PONE.0124555
Juan Peng, Zhengyong Xie, Liyang Cheng, Yuxin Zhang, Junyong Chen, Hongping Yu, Zehang Li, Huixing Kang, Paired design study by real-time PCR: miR-378* and miR-145 are potent early diagnostic biomarkers of human colorectal cancer BMC Cancer. ,vol. 15, pp. 158- 158 ,(2015) , 10.1186/S12885-015-1123-2
Wei Chen, Chuan Qin, General hallmarks of microRNAs in brain evolution and development RNA Biology. ,vol. 12, pp. 701- 708 ,(2015) , 10.1080/15476286.2015.1048954
Fang Li, Liyuan Zhang, Wei Li, Jieqiong Deng, Jian Zheng, Mingxing An, Jiachun Lu, Yifeng Zhou, Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway Oncotarget. ,vol. 6, pp. 6001- 6013 ,(2015) , 10.18632/ONCOTARGET.3469
Gero Doose, Maria Alexis, Rebecca Kirsch, Sven Findeiß, David Langenberger, Rainer Machné, Mario Mörl, Steve Hoffmann, Peter F. Stadler, Mapping the RNA-Seq trash bin: Unusual transcripts in prokaryotic transcriptome sequencing data RNA Biology. ,vol. 10, pp. 1204- 1210 ,(2013) , 10.4161/RNA.24972
Zhaoyong Li, Chuan Huang, Chun Bao, Liang Chen, Mei Lin, Xiaolin Wang, Guolin Zhong, Bin Yu, Wanchen Hu, Limin Dai, Pengfei Zhu, Zhaoxia Chang, Qingfa Wu, Yi Zhao, Ya Jia, Ping Xu, Huijie Liu, Ge Shan, Exon-intron circular RNAs regulate transcription in the nucleus Nature Structural & Molecular Biology. ,vol. 22, pp. 256- 264 ,(2015) , 10.1038/NSMB.2959
Simon J. Conn, Katherine A. Pillman, John Toubia, Vanessa M. Conn, Marika Salmanidis, Caroline A. Phillips, Suraya Roslan, Andreas W. Schreiber, Philip A. Gregory, Gregory J. Goodall, The RNA binding protein quaking regulates formation of circRNAs. Cell. ,vol. 160, pp. 1125- 1134 ,(2015) , 10.1016/J.CELL.2015.02.014
Xintian You, Irena Vlatkovic, Ana Babic, Tristan Will, Irina Epstein, Georgi Tushev, Güney Akbalik, Mantian Wang, Caspar Glock, Claudia Quedenau, Xi Wang, Jingyi Hou, Hongyu Liu, Wei Sun, Sivakumar Sambandan, Tao Chen, Erin M Schuman, Wei Chen, Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity Nature Neuroscience. ,vol. 18, pp. 603- 610 ,(2015) , 10.1038/NN.3975