Reduction in catheter-related infections after switching from povidone-iodine to chlorhexidine for the exit-site care of tunneled central venous catheters in children on hemodialysis

摘要: Only a few studies have investigated the optimal exit site management of tunneled central venous catheters (CVCs) in pediatric patients on chronic hemodialysis (HD). The aim this study was to assess efficacy chlorhexidine solutions and 5% povidone-iodine solution incidence CVC-related infections children HD. exit-site infection (ESI), tunnel (TI), bloodstream (BSI) assessed two groups CVCs. iodopovidone group consisted 14 CVCs used between 1 January 2011 30 June 2012 10 children, whose median age at time CVC placement 11.8 years (range 1.2-19.2): for care. From August 31 2014, 0.5% gluconate/70% isopropyl alcohol site, 2% spray hub 13 (chlorhexidine group), 1.2-19.2). Ten episodes ESI were diagnosed (incidence 3.4/1000 days), only one 0.36/1000 days, P = 0.008). One TI observed (0.34/1000 none group. BSIs decreased from 1.7/1000 days (5 cases) (1 case, P = 0.06) after switching chlorhexidine. Two lost due group, whereas no In comparison with povidone-iodine, use gluconate associated reduction ESI, TI, BSI