作者: T GILBERT , T SELLARO , S BADYLAK
DOI: 10.1016/J.BIOMATERIALS.2006.02.014
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摘要: Decellularized tissues and organs have been successfully used in a variety of tissue engineering/regenerative medicine applications, the decellularization methods vary as widely interest. The efficiency cell removal from is dependent on origin specific physical, chemical, enzymatic that are used. Each these treatments affect biochemical composition, ultrastructure, mechanical behavior remaining extracellular matrix (ECM) scaffold, which turn, host response to material. Herein, most commonly described, consideration give effects upon biologic scaffold