Influence of Ejection Fraction on Outcomes and Efficacy of Sacubitril/Valsartan (LCZ696) in Heart Failure with Reduced Ejection Fraction The Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure (PARADIGM-HF) Trial

作者: Scott D. Solomon , Brian Claggett , Akshay S. Desai , Milton Packer , Michael Zile

DOI: 10.1161/CIRCHEARTFAILURE.115.002744

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摘要: Background—The angiotensin receptor neprilysin inhibitor sacubitril/valsartan (LCZ696) reduced cardiovascular morbidity and mortality compared with enalapril in patients heart failure (HF) and...

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