Cryopreservation of the Germplasm of Animals Used in Biological and Medical Research: Importance, Impact, Status, and Future Directions

摘要: Abstract Molecular genetics and developmental biology have created thousands of new strains laboratory animals, including rodents, Drosophila, zebrafish. This process will accelerate. A decreasing fraction can be maintained as breeding colonies; hence, the others lost irretrievably unless their germplasm cryopreserved. Because increasingly critical role cryopreservation, because wide differences in success with which various forms cryopreserved species, National Institutes Health Center for Research Resources held a workshop on April 10–11, 2007, titled “Achieving High-Throughput Repositories Biomedical Germplasm Preservation.” The species concern were mouse, rat, domestic swine, rhesus monkey, Our review/commentary has several purposes. first is to summarize status cryopreservation from these assessed workshop. second discuss nature of...