Immunosafety and chronic toxicity evaluation of monomethoxypoly(ethylene glycol)-b-poly(lactic acid) polymer micelles for paclitaxel delivery

作者: Chang Li , Yan Shen , Chunmeng Sun , Nihad Cheraga , Jiasheng Tu

DOI: 10.3109/10717544.2014.920429

关键词:

摘要: … N 2 stream; the flask was sealed and maintained in an oil bath at 140 C under stirring for 6 h. … In this study, we successfully testified the hypo-toxicity of mPEG-PLA and low risk to trigger …

参考文章(18)
Ding Qu, Haijiao Lin, Nan Zhang, Jingwei Xue, Can Zhang, In vitro evaluation on novel modified chitosan for targeted antitumor drug delivery Carbohydrate Polymers. ,vol. 92, pp. 545- 554 ,(2013) , 10.1016/J.CARBPOL.2012.08.112
Li Li, Jun Ki Kim, Kang Moo Huh, Yong-kyu Lee, So Yeon Kim, Targeted delivery of paclitaxel using folate-conjugated heparin-poly(β-benzyl-l-aspartate) self-assembled nanoparticles Carbohydrate Polymers. ,vol. 87, pp. 2120- 2128 ,(2012) , 10.1016/J.CARBPOL.2011.10.030
Zhongshan Zhang, Quanbin Zhang, Jing Wang, Xuelian Shi, Jingjing Zhang, Houfang Song, Synthesis and drug release in vitro of porphyran carrying 5-Fluorouracil Carbohydrate Polymers. ,vol. 79, pp. 628- 632 ,(2010) , 10.1016/J.CARBPOL.2009.09.009
Xichen Zhang, John K. Jackson, Helen M. Burt, Development of amphiphilic diblock copolymers as micellar carriers of taxol International Journal of Pharmaceutics. ,vol. 132, pp. 195- 206 ,(1996) , 10.1016/0378-5173(95)04386-1
Yong Zhang, Meirong Huo, Jianping Zhou, Aifeng Zou, Weize Li, Chengli Yao, Shaofei Xie, DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles Aaps Journal. ,vol. 12, pp. 263- 271 ,(2010) , 10.1208/S12248-010-9185-1
Xuefei Zhang, Yuxin Li, Xuesi Chen, Xiuhong Wang, Xiaoyi Xu, Qizhi Liang, Junli Hu, Xiabin Jing, Synthesis and characterization of the paclitaxel/MPEG-PLA block copolymer conjugate. Biomaterials. ,vol. 26, pp. 2121- 2128 ,(2005) , 10.1016/J.BIOMATERIALS.2004.06.024
I. Jabbal Gill, A.N. Fisher, M. Hinchcliffe, J. Whetstone, N. Farraj, R. De Ponti, L. Illum, Cyclodextrins as protection agents against enhancer damage in nasal delivery systems II. Effect on in vivo absorption of insulin and histopathology of nasal membrane European Journal of Pharmaceutical Sciences. ,vol. 1, pp. 237- 248 ,(1994) , 10.1016/0928-0987(94)90017-5
Chun-Liang Lo, Chun-Kai Huang, Ko-Min Lin, Ging-Ho Hsiue, Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery Biomaterials. ,vol. 28, pp. 1225- 1235 ,(2007) , 10.1016/J.BIOMATERIALS.2006.09.050
XiuLing Zheng, Bing Kan, MaLing Gou, ShaoZhi Fu, Juan Zhang, Ke Men, LiJuan Chen, Feng Luo, YingLan Zhao, Xia Zhao, Preparation of MPEG-PLA nanoparticle for honokiol delivery in vitro. International Journal of Pharmaceutics. ,vol. 386, pp. 262- 267 ,(2010) , 10.1016/J.IJPHARM.2009.11.014