Thyroid transcription factors in development, differentiation and disease
作者： Lara P. Fernández , Arístides López-Márquez , Pilar Santisteban
关键词:
摘要: Collectively known as the thyroid transcription factors (TTFs), expression of NKX2-1, FOXE1, PAX8 and HHEX is essential for normal development maintenance adult gland. In this Review, authors discuss roles each TTFs in developing gland, well non-thyroid tissues. Mutations genes encoding can result a spectrum phenotypes, such dysgenesis cancer, which are also addressed.
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