Strong sequence conservation of African swine fever virus p72 protein provides the molecular basis for its antigenic stability
作者： M. Yu , C. J. Morrissy , H. A. Westbury
DOI: 10.1007/BF01718302
关键词:
摘要: The major capsid protein p72 of African swine fever virus (ASFV) has long been considered an important immunodominant antigen for serologic diagnosis. Here we describe the cloning and sequence analysis two p72-coding genes from ASFV strains Uganda (UGA) Dominican Republic-2 (DR2). Sequence comparison these genes, together with those other (BA71V E70), demonstrated that proteins are highly conserved (97.8% to 100% amino acid identity) in isolated different parts world. These results support previous observations indicating is antigenically stable, provide a useful molecular basis further development tests using this antigenic molecule.
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