Preoperative evaluation of patients with malignant pleural mesothelioma: role of integrated CT-PET imaging.

摘要: Malignant pleural mesothelioma (MPM) is an uncommon neoplasm arising from mesothelial cells of the pleura. The prognosis poor with a median survival 8 to 18 months after diagnosis. Multimodality regimens combining chemotherapy, radiotherapy, immunotherapy, and surgery are being used more frequently in patient management. Extrapleural pneumonectomy surgical treatment choice 10% 15% patients who present resectable disease reported prolong survival. Accurate staging important distinguish those requiring palliative therapy. Integrated computed tomography-positron emission tomography (CT-PET) increases accuracy overall MPM significantly improves selection for curative resection. Specifically, CT-PET detects extensive involvement than that shown by other imaging modalities particularly useful identifying occult distant metastases. This article reviews aspects performed initial according International Mesothelioma Interest Group system will emphasize appropriate role determining T, N, M descriptors.