Membrane potential and ion partitioning in an erythrocyte using the Poisson-Boltzmann equation.

作者: Nathalia S. V. Barbosa , Eduardo R. A. Lima , Mathias Boström , Frederico W. Tavares

DOI: 10.1021/ACS.JPCB.5B02215

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摘要: In virtually all mammal cells, we can observe a much higher concentration of potassium ions inside the cell and vice versa for sodium ions. Classical theories ignore specific ion effects difference in thermodynamic reference states between intracellular extracellular environments. Usually, this differential partitioning across membrane is attributed exclusively to active transport. Our aim investigate how dispersion forces contribute pumps an erythrocyte (red blood cell) as well correction chemical potential The ionic partition are analyzed by modified Poisson–Boltzmann equation, considering nonelectrostatic interactions macromolecules. Results show that calculated Lifshitz theory has only small influence with respect high K+ the...

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