Deoxynivalenol in chicken feed alters the vaccinal immune response and clinical biochemical serum parameters but not the intestinal and carcass characteristics.

摘要: Summary This study was conducted to investigate the impacts of deoxynivalenol (DON) feeding either alone or in combination with a microbial feed additive (MFA) on immune response viral vaccine and serum clinical chemical parameters. Forty 1-day-old boiler chicks were weighed randomly divided into four groups, 10 birds each group: (i) control group fed basal diet; (ii) DON diet artificially contaminated 10 mg DON/kg feed; (iii) + MFA supplemented 2.5 kg MFA/ton (iv) feed. At 35 days age, slaughtered blood collected for investigating antibody titre against infectious bronchitis virus (IBV) The results showed that reduced (p = 0.032) IBV, decreased (p = 0.005) level alanine transaminase (ALT) (4.2 ± 0.5 U/l) compared (6.4 ± 0.5 U/l), increased (p = 0.002) cholesterol concentration (144 ± 6 mg/dl) their counterparts (123 ± 5 mg/dl) (p = 0.074) amount circulating triglycerides (62.25 ± 7.50 mg/dl) controls (39.55 ± 4.74). These indicate dietary altered humoral affected biochemistry. However, did not affect IBV titre. Taken together, broilers produced an impairment success health birds.