作者: Mamoru Ohashi , Kazuyoshi Ogasawara , Hiroshi Fujioka , Yoshimi Shirai
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摘要: A fast-dissolving pharmaceutical composition comprising micronized (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3′-pyrrolidine-1,2′,3,5′-tetrone (hereinafter, referred to as AS-3201). The present has improved dissolution characteristics well a good bioavailability.