Inhibitors of integrin vla-4

作者: John W. Babich , Craig N. Zimmerman

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摘要: A complex, its stereoisomer or pharmaceutically acceptable salt has the formula (I), where:Formula wherein: W is a group that A, B, C: R1 hydrogen, alkyl alkoxy; R2 bond, hydrogen alkyl; R3, R4 and R5 are independently iodine, alkyl, alkoxy, hydroxyl, amino, aminoalkyl, dialkylamino, carboxyl; X C=O, O=C-O, CH2; Y CH2, O; m an integer ranging from 1 to 6; n 0 Metal represents metallic moiety comprising radionuclide; Chelate chelating coordinates with said radionuclide form complex.

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