Effect of demineralized bone matrix on bone growth within a porous HA material: a histologic and histometric study.
作者： Christopher J. Damien , J. Russell Parsons , Annamarie B. Preweit , Frank Huismans , Edwin C. Shors
DOI: 10.1177/088532829500900306
关键词:
摘要: Coralline hydroxyapatite (cHA) is an osteoconductive material currently being used as a bone graft substitute. Created by the hydrothermal conversion of calcium carbonate skeleton coral to hydroxyapatite, this has porous structure similar cancellous bone. Addition demineralized matrix (DBM) would conceivably create composite with both and osteoinductive properties. This pilot study evaluated healing rabbit cranial defects that had been filled cHA or augmented DBM gel formed adding glycerol particulate. Data from these were then compared unfilled previous study. Results indicated enhancement new formation increase in rate cHA-DBM composite. Further studies are warranted.
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