A convenient animal model for testing bone substitute materials.

摘要: There is consijerable interest in developing substitute materials for bone to perform the functions of autogenous grafts. However, a persistent problem finding suitable animal model which test biodegradable implants. This paper reviews requirements an ideal this purpose and discusses shortcomings existing procedures. A technique described that uses cranial vault rabbit allows accurate radiologic histologic assessment implant resorption ingrowth new bone.