Measurements of singlet oxygen in photodynamic therapy

作者: A. E. Profio , K-H Shu

DOI: 10.1117/12.978012

关键词:

摘要: Photochemical reactions are used in photodynamic therapy of cancer and other disease. The cytotoxic agent photochemotherapy is usually singlet oxygen. Thus measurements oxygen production or concentration may allow prediction the biological response. decrease fluorescence L-tryptophan because reaction with oxygen, absorbance a dye such as RNO subject to secondary oxidation by most common photosensitizer, dihematoporphyrin ether/ester (DHE) photobleaching, have been investigated solutions vitro. promising method for dosimetry response appears be photobleaching DHE.

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