New Lipid- and Glycolipid-Based Nanosystems for Targeted Gene Delivery: Cholenims, Glycoclips, Glycolipids and Chitosan
作者： R.I. Zhdanov , E.V. Bogdanenko , T.V. Zarubina , S.I. Dominova , G.G. Krivtsov
DOI: 10.1007/978-1-4020-6289-6_2
关键词:
摘要: Cationic lipid vesicles and polypeptides represent common non-viral gene delivery systems for in vitro vivo applications. New vectors targeted delivery, namely, mono-, di- tricholesterol derivatives of oligoethyleneimine, glycolipids chitosan are reported this chapter. Testing genotoxicity, cytotoxicity transfer activity against transformed monolayer suspension cell cultures is carried out all these mediators transfer. Experimental results show that GLYCOLIPID VI containing a lactose residue, which was used to form liposomes into tissues (using 14C-adenosine-labeled or plasmid DNA), expressed the affinity corresponding lipoplexes kidney, liver, spleen tissues. prospective tool designing new generation nonviral In addition, mCHIT preparation demonstrated high (β-Gal CSEAP plasmids) both lines
springer.com
sci-hub.st 参考文章(55)
Patrick Erbacher, Shaomin Zou, Thierry Bettinger, Anne‐Marie Steffan, Jean‐Serge Remy, Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability Pharmaceutical Research. ,vol. 15, pp. 1332- 1339 ,(1998) , 10.1023/A:1011981000671
SOUMENDU BHATTACHARYA, LEAF HUANG, CHAPTER 5.3 – Cationic liposome-DNA complexes in gene therapy Medical Applications of Liposomes. pp. 371- 394 ,(1998) , 10.1016/B978-044482917-7/50022-3
Shigehiro Hirano, Haruyoshi Seino, Yasutoshi Akiyama, Isao Nonaka, Chitosan: A Biocompatible Material for Oral and Intravenous Administrations Springer, Boston, MA. pp. 283- 290 ,(1990) , 10.1007/978-1-4899-0768-4_28
O. Yu. Abakumova, O. V. Podobed, T. A. Tsvetkova, I. V. Yakusheva, T. A. Moskvitina, L. I. Kondakova, D. G. Navasardyantz, A. E. Medvedev, Modulation of glutamate neurotoxicity in the transformed cell culture by monoamine oxidase inhibitors, clorgyline and deprenyl. Journal of Neural Transmission-supplement. ,vol. 52, pp. 87- 91 ,(1998) , 10.1007/978-3-7091-6499-0_10
Ivan F. Lamb, The Nineties and Beyond Defense Technical Information Center. ,(1990) , 10.21236/ADA223248
Michael Strauss, John A. Barranger, Concepts in gene therapy W. de Gruyter. ,(1997)
Florin Badea, Reaction mechanisms in organic chemistry ,(1977)
Charles G. Gebelein, Richard L. Dunn, Progress in Biomedical Polymers ,(1990)
Renat Zhdanov, Elena Bogdanenko, Alexey Moskovtsev, Olga Podobed, Nejat Düzgüneş, Liposome-mediated gene delivery: dependence on lipid structure, glycolipid-mediated targeting, and immunological properties. Methods in Enzymology. ,vol. 373, pp. 433- 465 ,(2003) , 10.1016/S0076-6879(03)73028-6
Demetrios Papahadjopoulos, D. D. Lasic, Medical applications of liposomes Elsevier. ,(1998)