Signal Transduction at the Single-Cell Level: Approaches to Study the Dynamic Nature of Signaling Networks

摘要: Signal transduction, or how cells interpret and react to external events, is a fundamental aspect of cellular function. Traditional study signal transduction pathways involves mapping signaling at the population level. However, population-averaged readouts do not adequately illuminate complex dynamics heterogeneous responses found single-cell Recent technological advances that observe response, computationally model pathways, experimentally manipulate now enable studying These studies will deeper insights into dynamic nature networks.