Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates.

摘要: The in-depth characterization of sex differences relevant to human physiology requires the judicious use a variety animal models and clinical data. Nonhuman primates (NHPs) represent an important experimental system that bridges rodent studies investigations. NHP have been especially useful in understanding role hormones development metabolism also allow elucidation effects pertinent dietary influences on disease states such as obesity diabetes. This chapter summarizes current state our androgen male female hypogonadism males polycystic ovary syndrome females. review will focus interaction between altered levels restriction excess, particular Western-style diet underlies significant pathophysiology.