Juvenile dermatitis herpetiformis versus "benign chronic bullous dermatosis of childhood." Are these immunologic diseases?

摘要: Seven cases of juvenile dermatitis herpetiformis have been investigated. Immunofluorescence and histologic studies were made in all jejunal biopsies three. Immunopathologic results positive including one that had previously reported to be negative. Two groups could distinguished according clinical criteria, response sulfapyridine, character the immunoglobulin deposits. The first corresponded (DH) adults, with characteristic lesions mucosa; second either bullous pemphigoid (BP), although majority without circulating antibasement-membrane antibodies, or a mixed type combined features DH BP. Repeated serial sections are essential for demonstrating immune question arises whether any immunologically negative "benign chronic dermatosis childhood" actually exist.