IMMUNO‐HISTOPATHOLOGY OF THE SKIN IN PEMPHIGOID

作者: R. H. CORMANE , E. SZABO

DOI: 10.1111/J.1365-2133.1970.TB15076.X

关键词:

摘要: SUMMARY.— The in vivo direct immunofluorescent (DIF) staining patterns of the skin surrounding lesions 5 patients suffering from pemphigoid are reported. It appeared that fine granular IgG deposits occur dermis and more closely packed junctional zone most biopsies examined. Only 1 case with a very high (anti-basement membrane) antibody titre showed conspicuous linear fluorescence basement membrane zone, while 2 other cases less litre both types patterns. impression was gained there is some relation between DIF pattern DH. The findings this study also favour concept dermatitis herpetiformis different disease entities; however existence intermediate cannot be ruled out. The advantages method discussed. An improved filter combination for blue narrow-band excitation rigid control conjugates used IF studies recommended.

参考文章(18)
ARTHUR ROOK, ERIC WADDINGTON, Pemphigus and pemphigoid. British Journal of Dermatology. ,vol. 65, pp. 425- 425 ,(1953) , 10.1111/J.1365-2133.1953.TB13181.X
J. R. PRAKKEN, M. J. WOERDEMAN, "Pemphigoid" (para-pemphigus): its relationship to other bullous dermatoses. British Journal of Dermatology. ,vol. 67, pp. 92- 97 ,(1955) , 10.1111/J.1365-2133.1955.TB12697.X
T. Chorzelski, S. Jabłońska, M. Blaszczyk, M. Jarzabek, Autoantibodies in Pemphigoid Dermatology. ,vol. 136, pp. 325- 334 ,(1968) , 10.1159/000254118
J. PIERARD, I. WHIMSTER, THE HISTOLOGICAL DIAGNOSIS OF DERMATITIS HERPETIFORMIS, BULLOUS PEMPHKIOTD AND ERYTHEMA MULTIFORME. British Journal of Dermatology. ,vol. 73, pp. 253- 266 ,(1961) , 10.1111/J.1365-2133.1961.TB14442.X
T.P. Chorzelski, R.H. Cormane, The presence of complement "bound" in vivo in the skin of patients with pemphigoid. Dermatology. ,vol. 137, pp. 134- 138 ,(1968) , 10.1159/000254042
T. CHORZELSKI, S. JABLOŃSKA, M. BLASZCZYK, IMMUNOPATHOLOGICAL INVESTIGATIONS IN THE SENEARUSHER SYNDROME (COEXISTENCE OF PEMPHIGUS AND LUPUS ERYTHEMATOSUS) British Journal of Dermatology. ,vol. 80, pp. 211- 217 ,(1968) , 10.1111/J.1365-2133.1968.TB11961.X
I. B. Sneddon, R. Church, Diagnosis and Treatment of Pemphigoid BMJ. ,vol. 2, pp. 1360- 1363 ,(1955) , 10.1136/BMJ.2.4952.1360
Robert E. Jordon, Basement Zone Antibodies in Bullous Pemphigoid JAMA: The Journal of the American Medical Association. ,vol. 200, pp. 751- 756 ,(1967) , 10.1001/JAMA.1967.03120220053008
R.H. Cormane, K. Holubar, Immunofluorescence staining properties of different conjugates. Dermatology. ,vol. 139, pp. 135- 144 ,(1969) , 10.1159/000253903