Mechanisms involved in the association between peridontal diseases and cardiovascular disease

摘要: Oral Diseases (2011) 17, 450–461 It is now well accepted that besides the cholesterol associated mechanisms of atherogenesis, inflammation plays a crucial role in all stages development atherosclerotic lesion. This ‘inflammation hypothesis’ raises possibility through systemic elevations pro-inflammatory cytokines, periodontal diseases might also contribute to and, therefore, atherogenesis. In fact, there evidence are with higher levels high-sensitivity C-reactive protein and low grade inflammation. phenomenon has been explained based on either infectious or inflammatory nature diseases. The purposes this article were review (1) suggesting for oral bacterial species, particularly pathogens, atherogenesis; (2) potential explaining an etiological bacteria atherosclerosis; (3) infections accompanied by heightened state inflammation; (4) sources biomarkers diseases; (5) effects therapy cardiovascular risk.