Prevention of Cervical Cancer in Women: Human Papillomavirus DNA Testing in Atypical Pap Smears
作者： Chiara Stefani
DOI: 10.4172/2324-8955.1000104
关键词:
摘要: 1Summary Human papillomavirus (HPV) is definitely recognized as the necessary cause for development of cancer uterine cervix and detection HPV-DNA in cervical samples demonstrated to own a significantly higher sensitivity towards preneoplastic lesions than conventional cytology (Pap test). Screening, management atypical Pap tests follow up treated patients, represent optimal settings where testing has been clinical value. Atypical account cases which cytological alterations cannot clearly be attributed neither negative nor positive cytology; these have very close 100% identifying patients with an histologically proven intraepithelial lesion high grade (CIN2-CIN3). Despite this, specificity lacks significance referral rate second-level colposcopy too high. Different options tested improve overall performance equivocal present paper aims collect data from recent literature, order better clarify state art this particular aspect prevention.
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