The state of the art of odorant receptor deorphanization: A report from the orphanage

作者: Zita Peterlin , Stuart Firestein , Matthew E. Rogers

DOI: 10.1085/JGP.201311151

关键词:

摘要: … The odorant receptors (ORs) provide our main gateway to sensing the … odorants, work as an ensemble to produce a distributed activation code that is presumably unique to each odorant…

参考文章(121)
Da Yu Lin, Shao-Zhong Zhang, Eric Block, Lawrence C. Katz, Encoding social signals in the mouse main olfactory bulb. Nature. ,vol. 434, pp. 470- 477 ,(2005) , 10.1038/NATURE03414
Sayako Katada, Takao Nakagawa, Hiroshi Kataoka, Kazushige Touhara, Odorant response assays for a heterologously expressed olfactory receptor Biochemical and Biophysical Research Communications. ,vol. 305, pp. 964- 969 ,(2003) , 10.1016/S0006-291X(03)00863-5
P. C. Lai, B. Guida, J. Shi, C. J. Crasto, Preferential binding of an odor within olfactory receptors: a precursor to receptor activation. Chemical Senses. ,vol. 39, pp. 107- 123 ,(2014) , 10.1093/CHEMSE/BJT060
Lars Ellgaard, Ari Helenius, Quality control in the endoplasmic reticulum Nature Reviews Molecular Cell Biology. ,vol. 4, pp. 181- 191 ,(2003) , 10.1038/NRM1052
Sarah E. Repicky, Charles W. Luetje, Molecular receptive range variation among mouse odorant receptors for aliphatic carboxylic acids. Journal of Neurochemistry. ,vol. 109, pp. 193- 202 ,(2009) , 10.1111/J.1471-4159.2009.05925.X
Rafi Haddad, Rehan Khan, Yuji K Takahashi, Kensaku Mori, David Harel, Noam Sobel, A metric for odorant comparison. Nature Methods. ,vol. 5, pp. 425- 429 ,(2008) , 10.1038/NMETH.1197
Sulagna Ghosh, Stephen D. Larson, Hooman Hefzi, Zachary Marnoy, Tyler Cutforth, Kartheek Dokka, Kristin K. Baldwin, Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons Nature. ,vol. 472, pp. 217- 220 ,(2011) , 10.1038/NATURE09945
Peter C. Lai, Gautam Bahl, Maryse Gremigni, Valery Matarazzo, Olivier Clot-Faybesse, Catherine Ronin, Chiquito J. Crasto, An olfactory receptor pseudogene whose function emerged in humans: a case study in the evolution of structure–function in GPCRs Journal of Structural and Functional Genomics. ,vol. 9, pp. 29- 40 ,(2008) , 10.1007/S10969-008-9043-X
C. F. Bush, R. A. Hall, Olfactory receptor trafficking to the plasma membrane Cellular and Molecular Life Sciences. ,vol. 65, pp. 2289- 2295 ,(2008) , 10.1007/S00018-008-8028-Z