Enantioselective extraction of (d)-phenylalanine from racemic (dl)-phenylalanine using chiral emulsion liquid membranes

摘要: Abstract A chiral emulsion liquid membrane was developed using copper(II) N- decyl -( l )- hydroxyproline as a carrier in hexanol:decane solvent. Enantioselective differential transport of (D)-phenylalanine from racemic ( d/l )-phenylalanine demonstrated. The maximum experimental enantioselectivity observed the systems studied 2.4, although this tended to decrease with time due mass action effect. use low source phase pH, high hexanol and Paranox 106 were found maximise enantioselective transport. simple external interfacial reaction limited model characterise initial equilibrium stages extraction reasonably well. former observation be important highest enantioselectivities early extraction. Between these extraction, diffusion dominating transfer resistance.