Factors influencing the insulin space in cerebral cortex slices from adult and 7-day-old rats.

摘要: The inulin spaces and swelling of brain cortex slices from adult 7-day-old rats were measured under differing experimental conditions. At 37 degrees C penetrated into larger compartments than at 0 in both age groups. the space increased with decreasing concentration medium. did not depend on concentration. diminished increasing concentrations inulin. Anaerobic conditions, 0.2, 1.0 mmol/l sodium cyanide 0.1 dinitrophenol reduced caused slices. iodoacetate was ineffective. In anaerobic conditions change significantly as a function A serious disadvantage an indicator extracellular is that its size depends used. itself may influence to be measured. Inulin also osmotically inactive considerably reduces