Reduced tyrosine hydroxylase activity in nigrostriatal system of sinoaortic-denervated rats.

作者: Natalie Alexander , Yoko Hirata , Toshiharu Nagatsu

DOI: 10.1016/0006-8993(84)90724-8

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摘要: Tyrosine hydroxylase activity was measured in the caudate nucleus and substantia nigra (pars compacta) of sinoaortic-denervated (SAD) sham-operated (SO) rats 3 days after operation. The SAD groups had approximately a 50%, statistically significant, reduction enzyme both regions also significant dopamine nucleus. These results suggest probable link between cortico-somatomotor integration neural input from arterial baroreceptor pathways.

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