In vitro antimicrobial activity of oxidized regenerated cellulose against antibiotic-resistant microorganisms.
作者： Daniel Spangler , Stephen Rothenburger , Kien Nguyen , Hanuman Jampani , Scott Weiss
DOI: 10.1089/109629603322419599
关键词:
摘要: Background: The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), broad-spectrum physiological detriment to survival known cause surgical infections. purpose this study was examine the antimicrobial effect ORC against antibiotic-resistant organisms. Methods: products were challenged with ATCC reference strains and clinical isolates methicillin-resistant Staphylococcus aureus (MRSA), epidermidis (MRSE), vancomycin-resistant Enterococcus (VRE), penicillin-resistant Streptococcus pneumoniae (PRSP), non-resistant S. Pseudomonas aeruginosa. Samples three (SURGICEL* absorbable hemostat, SURGICEL* Fibrillar SURGICEL NU-KNIT* hemostat (registered *Trademark Ethicon) identified, respectively, as ORC-R, ORC-F, ORC...
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