Novel IL-3 antibodies and their use in diagnosis and treatment of diseases or malfunctions associated with elevated levels of IL-3

作者: Kerstin Renner , Matthias Mack , Hilke Brühl

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摘要: Novel anti-IL-3 antibodies or fragments constructs thereof according to the present invention specifically bind an epitope contained within N-terminal 20 amino acids of acid sequence human IL-3 SEQ ID No. 1, and preferably a motif SWVN. The can be used in diagnostic methods for determination levels body fluids, corresponding ELISA assays, but also pharmaceutical compositions treatment prevention diseases which are associated with elevated patient, especially rheumatoid arthritis.

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