N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl) -n-phenylamines as antiproliferative compounds

作者: Gavin Wood , Christopher Meades , Peter Martin Fischer , Andrew Osnowski , Shudong Wang

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摘要: The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and use as inhibitors of cyclin-dependent kinases (CDKs) hence in the treatment proliferative disorders such cancer, leukaemia, psoriasis like.

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