作者: Jonathan Shuster , Jan van Eys
DOI: 10.1016/S0197-2456(83)80026-9
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摘要: In randomized trials, the better therapy may depend on values of a prognostic factor. This article presents methodology for subdividing target population into three subsets: one region superiority each treatment, and uncertainty. The basis such subdivision is treatment by factor interaction. importance this analysis in group trial sequences discussed briefly.