Positron Emission Tomography in Diffuse Low-Grade Gliomas

摘要: Contrast-enhanced MRI is currently the method of choice for diagnosis diffuse low-grade gliomas and provides an excellent depiction structural changes in brain. Nevertheless, delineation tumor from normal brain tissue non-specific abnormalities on such as edema or treatment-related can be difficult. Positron-Emission-Tomography (PET) additional information metabolism helpful many clinical situations. In particular, PET using radiolabeled amino acids has a wide range applications helps to solve number issues. At initial diagnosis, acid may estimate prognosis glioma optimize patient counseling. Furthermore, improves targeting biopsy extent, which also resection planning radiotherapy. further course disease, allows sensitive monitoring treatment response, early detection recurrence, improved differentiation recurrence changes. past, had only limited availability due low scanners use radiopharmaceuticals with short half-life. recent years, however, hospitals increased considerably. novel tracers labeled positron emitters longer half-life have been developed clinically validated allow more efficient cost-effective application. These developments well-documented diagnostic performance suggest that its application continues spread available routine technique certain indications near future.