摘要: Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and typically resistant to most (sometimes all) antibiotics. We now face global CPO pandemic of high mortality. In this issue the Journal Clinical Microbiology, Karlowsky et al. (J Clin Microbiol 55:1638-1649, 2017, https://doi.org/10.1128/JCM.02316-16) report results an extensive surveillance study provide much-needed information enhances our understanding carbapenemase-producing Enterobacteriaceae (CPE) which will be valuable for development improved strategies CPE control therapy infections.