Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages

作者: M.C. Bibby

DOI: 10.1016/J.EJCA.2003.11.021

关键词:

摘要: … identified only a limited number of useful agents that are active clinically at well tolerated … role of the tumour site on response to therapeutic agents, it is likely that the use of orthotopic …

参考文章(42)
Jerald J. Killion, Robert Radinsky, Isaiah J. Fidler, Orthotopic models are necessary to predict therapy of transplantable tumors in mice Cancer and Metastasis Reviews. ,vol. 17, pp. 279- 284 ,(1998) , 10.1023/A:1006140513233
Jacqueline Plowman, Donald J. Dykes, Melinda Hollingshead, Linda Simpson-Herren, Michael C. Alley, Human Tumor Xenograft Models in NCI Drug Development Anticancer Drug Development Guide. pp. 101- 125 ,(1997) , 10.1007/978-1-4615-8152-9_6
Robert M. Hoffman, Fertile Seed and Rich Soil Anticancer Drug Development Guide. pp. 127- 144 ,(1997) , 10.1007/978-1-4615-8152-9_7
George Pettit, P. A. Cooper, S. E. Holwell, J. W. Lippert, M. J. Thompson, M. C. Bibby, S. W. Martin, Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate. Anticancer Research. ,vol. 22, pp. 3933- 3940 ,(2002)
Epie Boven, Benjamin Winograd, The Nude Mouse in Oncology Research ,(1991)
Takashi Chishima, A. R. Moossa, Hiroshi Shimada, Robert M. Hoffman, Hiroyuki Yamaoka, Yohei Miyagi, Xiaoen Wang, Cancer Invasion and Micrometastasis Visualized in Live Tissue by Green Fluorescent Protein Expression Cancer Research. ,vol. 57, pp. 2042- 2047 ,(1997)
M. H. Tan, E. D. Holyoke, M. H. Goldrosen, Murine Colon Adenocarcinoma: Syngeneic Orthotopic Transplantation and Subsequent Hepatic Metastases Journal of the National Cancer Institute. ,vol. 59, pp. 1537- 1544 ,(1977) , 10.1093/JNCI/59.5.1537
Nadia El Hilali, Nuria Rubio, Mercedes Martinez-Villacampa, Jerónimo Blanco, Combined Noninvasive Imaging and Luminometric Quantification of Luciferase-Labeled Human Prostate Tumors and Metastases Laboratory Investigation. ,vol. 82, pp. 1563- 1571 ,(2002) , 10.1097/01.LAB.0000036877.36379.1F
M C Bibby, Making the most of rodent tumour systems in cancer drug discovery. British Journal of Cancer. ,vol. 79, pp. 1633- 1640 ,(1999) , 10.1038/SJ.BJC.6690261