BCL-2 FAMILY PROTEINS : STRATEGIES FOR OVERCOMING CHEMORESISTANCE IN CANCER

作者: John C. Reed

DOI: 10.1016/S1054-3589(08)61070-4

关键词:

摘要: … beginning to suggest strategies for potentially abrogating the … For example, antisense oligonucleotides and expression … These agents target enzymes required for nucleotide precursor …

参考文章(189)
Andrews Dw, Chatterjee D, Reddy Ep, Das R, Identification of a novel Bcl-2 related gene, BRAG-1, in human glioma. Oncogene. ,vol. 12, pp. 947- 951 ,(1996)
D. J. McConkey, S. Brisbay, T. J. McDonnell, A. Fernandez, M. C. Marin, A. C. Von Eschenbach, L M Buja, Roger J Bick, M. Snuggs, M. J. Keating, Apoptosis suppression by bcl-2 is correlated with the regulation of nuclear and cytosolic Ca2+ Oncogene. ,vol. 12, pp. 2259- 2266 ,(1996)
Chittenden T, Avery Bj, Subramanian T, Gallo Gj, Houghton Ab, Boyd Jm, Ebb Rg, Malstrom S, Elangovan B, Lutz Rj, Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene. ,vol. 11, pp. 1921- 1928 ,(1995)
W. Zhu, A. Cowie, G. W. Wasfy, L. Z. Penn, B. Leber, D. W. Andrews, Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. The EMBO Journal. ,vol. 15, pp. 4130- 4141 ,(1996) , 10.1002/J.1460-2075.1996.TB00788.X
Shaun P. Holmgreen, Suzanne Cory, Elizabeth Baker, Leonie Gibson, Jerry M. Adams, Nancy A. Jenkins, Neal G. Copeland, Grant R. Sutherland, David C.S. Huang, Ora Bernard, bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene. ,vol. 13, pp. 665- 675 ,(1996)
Sun Shim Choi, In-Chul Park, Jin Won Yun, Young Chul Sung, Seok-Il Hong, Hee-Sup Shin, A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. Oncogene. ,vol. 11, pp. 1693- 1698 ,(1995)
T. Chittenden, C. Flemington, A. B. Houghton, R. G. Ebb, G. J. Gallo, B. Elangovan, G. Chinnadurai, R. J. Lutz, A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. The EMBO Journal. ,vol. 14, pp. 5589- 5596 ,(1995) , 10.1002/J.1460-2075.1995.TB00246.X
G. Krystal, J. M. Ben-Ezra, M. M. Grimes, M. J. Kornstein, Small cell carcinomas of the lung express the Bcl-2 protein. American Journal of Pathology. ,vol. 145, pp. 1036- 1040 ,(1994)
Valerie P. Castle, Mukund Dole, Gabriel Nuñez, Kathleen P. Heidelberger, Judith Bromberg, Xianglan Ou, Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification. American Journal of Pathology. ,vol. 143, pp. 1543- 1550 ,(1993)
AJ Minn, CM Rudin, LH Boise, CB Thompson, Expression of Bcl-xL Can Confer a Multidrug Resistance Phenotype Blood. ,vol. 86, pp. 1903- 1910 ,(1995) , 10.1182/BLOOD.V86.5.1903.BLOODJOURNAL8651903