Synthesis of N-quinonyltaurines

作者: S. Bittner , S. Gorohovsky , G. Temtsin-Krayz

DOI: 10.1007/S00726-002-0407-4

关键词:

摘要: Both 1,4-benzoquinones and 1,4-naphthoquinones were attached to the non-proteinogenic amino acid taurine form N-quinonyl derivatives. The products formed via direct Michael-like addition or by substitution of a good leaving group. An attempt bridge two moieties an ureido spacer resulted in formation bis-quinonylamino isocyanurate derivative. Preliminary MO calculations provided internal ground-state geometries orbital coefficients HOMO levels representing conjugates.

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