Enzymatic electrochemical biosensors for in situ neurochemical measurement
作者： Cong Pan , Huan Wei , Zhongjie Han , Fei Wu , Lanqun Mao
DOI: 10.1016/J.COELEC.2019.12.008
关键词:
摘要: Abstract In situ real-time electroanalysis of neurochemical concentrations offers rich information for exploring the spatiotemporal heterogeneity molecular events in nervous system. Biosensors with enzyme-modified sensing interfaces are well suited measuring neurologically important but electroinactive species, greatly broadening range electrochemically detectable analytes. Minimally invasive micro/nanoelectrodes bearing enzymatically functional layers used to fulfill requirements in situ studies at various neuronal levels as discussed this minireview. Current achievements on nanoelectrode biosensors intracellular analysis and microelectrode single-cell in vivo highlighted enlighten emerging trends realm, views prospective enzymatic provided end.
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