Effects of stress in early life on immune functions in rats with asthma and the effects of music therapy.
作者： Yanxia Lu , Meng Liu , Shousen Shi , Hong Jiang , Lejin Yang
DOI: 10.3109/02770901003801964
关键词:
摘要: Objective. Although studies have shown that psychological stress has detrimental effects on bronchial asthma, there are few objective data whether early-life stress, as early postnatal psychosocial environment, a long-lasting effect adult asthma and the potential pathophysiologic mechanism. This study aims to examine immune function hypothalamic-pituitary-adrenal (HPA) axis responses in asthmatic rats experienced life ameliorative of music therapy these parameters. Methods. Forty male Wistar rat pups were randomly assigned group, adulthood-stressed childhood-stressed control group. Restraint Mozart's Sonata K.448 applied ovalbumin (OVA)-induced establish models. The levels serum corticosterone examined both childhood after adulthood OVA challenge...
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