Benzoyl Urea Derivatives

摘要: The new benzoyl urea derivatives of formula (I) wherein the meaning X and Y independently are hydrogen atom, hydroxy, benzyloxy, amino, nitro, C1-C4 alkylsulfonamido optionally substituted with a halogen atom or atoms, alkanoylamido alkoxy, aroyl-carbamoyl alkyl alkoxycarbonyl group, neighboring groups form together one more identical different additional hetero —CH═ and/or —CH2— an 4-7 membered homo- heterocyclic ring, preferably morpholine, pyrrole, pyrrolidine, oxo- thioxo-pyrrolidine, pyrazole, pyrazolidine, imidazole, imidazolidine, thioxo-imidazole 1,4-oxazine, oxazole, oxazolidine, triazole, thioxo-oxazolidine, 3-oxo-1,4-oxazine V Z cyano, alkyl, trifluoromethyl, hydroxy esterized carboxyl W is oxygen as well alkylene, C2-C4 alkenylene, aminocarbonyl, —NH—, —N(alkyl)-, —CH2O—, —CH2S—, —CH(OH)—, —OCH2— group—, when dotted bonds ( ) represent simple C—C then U group alkylene alkenylene can further double bond in this case means electron pair, which participate optical antipodes, racemates salts thereof highly effective selective antagonists NMDA receptor, moreover most compounds antagonist NR2B subtype receptor. Furthermore objects present invention pharmaceutical compositions containing antipodes active ingredients processes for producing these compositions.