Associations of Plasma Copper, Magnesium, and Calcium Levels with Blood Pressure in Children: a Cross-sectional Study

摘要: Studies of the relationship copper (Cu), magnesium (Mg), and calcium (Ca) levels with blood pressure in children are limited. This cross-sectional study included 443 aged 6–9 years from Guangzhou, China. Plasma concentrations Cu, Mg, Ca were measured by inductively coupled plasma mass spectrometry. Systolic (SBP) diastolic (DBP) an electronic sphygmomanometer. Elevated SBP DBP defined as 90th percentile or greater (age sex specific) reference values for Chinese children. Abnormal (ABP) was elevated and/or DBP. The Cu concentration positively correlated pressure, body index (BMI), C-reactive protein (CRP) level, whereas Mg negatively SBP. A higher (T3 vs. T1) associated a risk ABP (odds ratio (OR) 2.55, 95% confidence interval (CI) 1.20 to 5.40). In contrast, top tertiles (OR 0.42, CI 0.18 0.98) 0.28, 0.11 0.70) showed lower risks than those bottom tertiles. Path analysis that CRP BMI mediated associations between ABP. We found related 6–9 years. ABP, association BMI.