Generalised muscular hyperalgesia in chronic whiplash syndrome.

摘要: The whiplash syndrome has immense socio-economic impact. Despite extensive studies over the past years, mechanisms involved in maintaining pain chronic patients are poorly understood. aim of present experimental study was to examine muscular sensibility areas within and outside region trauma. Eleven 11 sex age matched control subjects were included study. Before experiment, had neck shoulder with radiating arm. Five reported that more widespread. somatosensory infraspinatus, brachioradial, anterior tibial muscles assessed by pressure stimulation, pin-prick cotton swap stimulation. Infusion hypertonic saline (5.85%, 0.5 ml) into infraspinatus performed assess referred pattern. saline-induced muscle intensity on a continuous visual analogue scale (VAS). distribution drawn an anatomical map. thresholds significantly lower (P<0. 01) compared controls: (mean 152.2 vs. 172.7 kPa), brachioradial 70.0 363.8 497.8 kPa). skin stimulation not different between controls. caused higher VAS scores longer duration (P<0.01). area under VAS-time curve (P<0.01) increased after injection 4138.1 780.0 cm s) 4370.8 978.7 s). infusion local defined as located around site area. larger In group, found at dorsal aspect ankle. contrast, quite widespread patient group both distal proximal areas. study, hyperalgesia large traumatised findings suggest generalised central hyperexcitability suffering from syndrome. This indicates might be considered neurogenic type pain, new pharmacological treatments should investigated accordingly.