Recombinant Production of Self-Assembling Peptides

作者: Michael J. McPherson , Kier James , Stuart Kyle , Stephen Parsons , Jessica Riley

DOI: 10.1016/S0065-2377(08)00204-4

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摘要: Abstract This chapter focusses upon the current capacity for recombinant production of both structural proteins and peptides, including those capable self-assembly. The prospects large-scale to deliver quantities required many engineering applications. Advantages disadvantages various protein expression systems will be presented with particular empthasis on microbial plant-based system. Tools assisting in downstream processing recovery peptides considered. One applications self-assembling is tissue matrices. To date there are few examples these discussed. We also consider successful naturally occurring extracellular matrix bioactive as offer important insights into development future peptide production.

参考文章(135)
Stefan Schillberg, Sabine Zimmermann, Andreas Voss, Rainer Fischer, Apoplastic and cytosolic expression of full-size antibodies and antibody fragments in Nicotiana tabacum. Transgenic Research. ,vol. 8, pp. 255- 263 ,(1999) , 10.1023/A:1008937011213
Brandy De Cosa, William Moar, Seung-Bum Lee, Michael Miller, Henry Daniell, Overexpression of the Bt cry2Aa2 operon in chloroplasts leads to formation of insecticidal crystals Nature Biotechnology. ,vol. 19, pp. 71- 74 ,(2001) , 10.1038/83559
E.R. Plunkett, Handbook of Industrial Toxicology ,(1976)
Ajay Kohli, Richard M Twyman, Rita Abranches, Eva Wegel, Eva Stoger, Paul Christou, Transgene integration, organization and interaction in plants Plant Molecular Biology. ,vol. 52, pp. 247- 258 ,(2003) , 10.1023/A:1023941407376
Umaporn Silphaduang, Edward J. Noga, Peptide antibiotics in mast cells of fish Nature. ,vol. 414, pp. 268- 269 ,(2001) , 10.1038/35104690
Bao-Cun Li, Shuang-Quan Zhang, Wen-Bing Dan, Yu-Qing Chen, Peng Cao, Expression in Escherichia coli and purification of bioactive antibacterial peptide ABP-CM4 from the Chinese silk worm, Bombyx mori Biotechnology Letters. ,vol. 29, pp. 1031- 1036 ,(2007) , 10.1007/S10529-007-9351-4
Henry Daniell, Stephen J Streatfield, Keith Wycoff, Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants Trends in Plant Science. ,vol. 6, pp. 219- 226 ,(2001) , 10.1016/S1360-1385(01)01922-7
Alessandra Girotti, Javier Reguera, José Carlos Rodríguez-Cabello, Francisco Javier Arias, Matilde Alonso, Ana Ma Testera, Design and bioproduction of a recombinant multi(bio)functional elastin-like protein polymer containing cell adhesion sequences for tissue engineering purposes. Journal of Materials Science: Materials in Medicine. ,vol. 15, pp. 479- 484 ,(2004) , 10.1023/B:JMSM.0000021124.58688.7A
Glynis Giddings, Transgenic plants as protein factories. Current Opinion in Biotechnology. ,vol. 12, pp. 450- 454 ,(2001) , 10.1016/S0958-1669(00)00244-5