Pigmentary and cutaneous risk factors for non-melanocytic skin cancer—A case-control study

摘要: The roles of ethnic origin, pigmentray traits, sun sensitivity and other cutaneous characteristics as risk factors for basal-cell carcinoma (BCC) squamous-cell (SCC) were examnied in a case-control study prevalent incident cases histopathologically confirmed skin cancers. Two hundred twenty six BCC, 45 SCC 1,015 controls with no lesions identified population-based survey cancer 1987 Geralditon, Western Australia. both cancers was higher nativeborn Australians than migrants. BCC decreased increasing age at arrival Southern European ancestry strongly protective against (for any southern grandparents) (no case had granparetns origin). Inability to tan the strongest pigmentary factor SCC. Among Factors that incorporated measure exposure well sensitivity, freckling on arm childhood important cancers, number moles back forearm colour having permanent difference between neck adjacent protected areas measures damage skin, solar elastosis strong SCC, loss fine texture sink hands (as measured by microtopography) telangiectasia face When all variables each examined together single model age, sex, migrant status or Australia, ethnicity, inability tan, neck, independently significant elatosis sifnificant effects origin remeained models incorporating these factors. A history ever acne warts