Chemical and biological properties of lipopolysaccharides from Fusobacterium necrophorum biovar A and biovar B strains.
作者： Takeshi INOUE , Masamitsu KANOE , Naoaki GOTO , Kendo MATSUMURA , Keiji NAKANO
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摘要: In order to elucidate factors influencing the virulence of F.necrophorum, studies were performed on chemical and biological properties lipopolysaccharides (LPSs) obtained from F.necrophorum VPI 2891 (FN 2891) which was biovar A virulent, 130 130) B avirulent. Chemical analyses revealed marked differences in contents hexose (21.5% as glucose FN LPS 66.2% LPS), aminosugar (12.9% glucosamine-HCI 0.9% LPS) lipid (34.0% 4.2% LPS). more toxic than lethal effect 10 day-old chick embryos, hemorrhagic necrosis solid tumor (Sarcoma 180), febrile response rabbits local Shwartzman reaction. No observed immunogenicity Limulus lysate test. These results indicated possibility that one related F.necrophorum.
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